Vitamin C: A Comprehensive Review of Its Role in Health, Disease Prevention, and Therapeutic Potential
Since Albert Szent-Györgyi discovered it and it became used in treating scurvy, vitamin C has attracted interest in many studies due to its unique properties. It is an important cofactor in the synthesis of collagen and hormones, and it is in...
Alberts A, Moldoveanu ET, Niculescu AG et al. — Molecules (Basel, Switzerland)
Effect of High-Dose Vitamin C on Tendon Cell Degeneration-An In Vitro Study
Tendinopathy is an aging-related disease, often caused by micro-scarring and degeneration due to overuse or trauma. Ascorbic acid (vitamin C) supplementation is reported to be a useful treatment for tendinopathy recovery. We compared the inhibitor...
Ueda S, Ichiseki T, Shimasaki M et al. — International journal of molecular sciences
[Vitamin C and its derivatives in maintaining the good skin condition]
Vitamin C is one of the most important and necessary nutrient for human health, which has great potential as cosmeceutic, which protects health and the skin good condition. Thru the collagen biosynthesis stimulation it affects to the physiology of...
Goik U — Postepy biochemii
A review of topical vitamin C derivatives and their efficacy
Vitamin C is a popular ingredient in over-the-counter cosmeceuticals due to its many biological functions in maintaining and improving skin health by treating UV damage, improving discoloration, and boosting collagen production. Several chemically...
Enescu CD, Bedford LM, Potts G et al. — Journal of cosmetic dermatology
Vitamin C epigenetically controls osteogenesis and bone mineralization
Vitamin C deficiency disrupts the integrity of connective tissues including bone. For decades this function has been primarily attributed to Vitamin C as a cofactor for collagen maturation. Here, we demonstrate that Vitamin C epigenetically orches...
Thaler R, Khani F, Sturmlechner I et al. — Nature communications
Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications
OBJECTIVE: This review article details the main mechanisms of action and clinical applications of topical vitamin C on the skin, including its antioxidative, photoprotective, antiaging, and antipigmentary effects. DESIGN: A PubMed search for the r...
Al-Niaimi F, Chiang NYZ — The Journal of clinical and aesthetic dermatology
Vitamin C in surgical sepsis
The current review discusses the supplemental use of vitamin C as an adjunct in the management of sepsis and septic shock.
Anand T, Roller LK, Jurkovich GJ — Current opinion in critical care
The Roles of Vitamin C in Skin Health
The primary function of the skin is to act as a barrier against insults from the environment, and its unique structure reflects this. The skin is composed of two layers: the epidermal outer layer is highly cellular and provides the barrier functio...
Pullar JM, Carr AC, Vissers MCM — Nutrients
Vitamin C-enriched gelatin supplementation before intermittent activity augments collagen synthesis
Musculoskeletal injuries are the most common complaint in active populations. More than 50% of all injuries in sports can be classified as sprains, strains, ruptures, or breaks of musculoskeletal tissues. Nutritional and/or exercise interventions ...
Shaw G, Lee-Barthel A, Ross ML et al. — The American journal of clinical nutrition
Vitamin C: a wound healing perspective
Vitamin C, also known as ascorbic acid (AA), is involved in all phases of wound healing. In the inflammatory phase it is required for neutrophil apoptosis and clearance. During the proliferative phase, AA contributes towards synthesis, maturation,...
Moores J — British journal of community nursing