Surgical recovery takes the teamwork of the patient, surgeon, therapist, family, and friends. But a true multimodal approach to recovery has been missing. We built Truthe to deliver that, combining physician-formulated nutrition and peptide therapy into one integrated protocol, designed by orthopaedic surgeons for orthopaedic patients.
Chad M. Ferguson, MD — Orthopedic Surgery
Most peptide companies are run by wellness entrepreneurs and bodybuilders. This one is run by a surgeon.
Read our medical philosophy →
J. Kent Ellington, MD, FAAOS — Orthopedic Surgery
Award-winning orthopedic foot & ankle surgeon. 18 patents in implant design. Associate Professor of Orthopaedics at Atrium Health. OrthoCarolina, Charlotte.
ORTHO CLINICAL PARTNERHOW IT WORKS.
Connect through your surgeon
Your orthopedic surgeon or sports medicine physician partners with Truthe Ortho to coordinate your recovery care. Every patient enters through a qualified physician who knows your case.
A Truthe Partner Provider designs your protocol
A Truthe Partner Provider reviews your medical history, current medications, recovery timeline, and goals — then designs a targeted peptide protocol specific to your condition.
Pharmacy compounds and ships
Your protocol is compounded by an FDA-registered U.S. pharmacy with cGMP certification. Every batch is tested for purity, sterility, and potency. Shipped directly to you with complete dosing instructions.
WHO THIS IS FOR
Built for patients with orthopedic conditions — surgical and non-surgical.
Truthe Ortho serves orthopedic patients across the full healing spectrum: acute injury, chronic stable conditions, pre-operative loading, and post-operative recovery. Whether you've had a recent rotator cuff repair, you're managing chronic knee osteoarthritis, you're loading before a planned ACL reconstruction, or you're a non-operative tendinopathy patient who has stalled on conservative care — your protocol is designed by a Provider for your specific situation. Prescribed by licensed Truthe Partner Providers, compounded by FDA-registered U.S. pharmacies, monitored throughout your protocol.
WHAT TO EXPECT.
WEEK 1-2
ACUTE PHASE
Protocol begins per surgeon clearance. Focus: inflammation management, wound protection, initial tissue signaling.
WEEK 3-4
PROLIFERATIVE PHASE
Active tissue repair. Peptides support angiogenesis (new blood vessel formation), fibroblast migration, and organized collagen deposition at the surgical site.
WEEK 5-8
REMODELING PHASE
Tissue maturation and strengthening. Protocol may adjust based on imaging, clinical assessment, and your subjective recovery progress.
WEEK 9-12
RESTORATION PHASE
Final protocol phase. Focus shifts to functional recovery, scar quality optimization, and return-to-activity preparation. Physician reassessment and protocol completion.
PROTOCOLS.
Four protocols. Each designed by Providers for orthopedic readiness, recovery, reconstruction, and daily baseline. Each built on evidence.
READY
Pre-Surgical OptimizationFor patients who need to lose weight before surgery. Surgeons often require BMI targets — under 35 for joint replacement, under 30 for spine fusion — before clearing elective procedures. READY protocols combine structured nutrition, supplementation, and when clinically indicated, GLP-1 receptor agonist therapy to help patients reach surgical clearance.
RECOVER
Orthopedic RecoveryFor patients recovering from orthopedic injury or surgery. Whether post-operative or managing a chronic musculoskeletal condition, RECOVER protocols support tendon, ligament, muscle, and joint healing with BPC-157 and TB-500 plus targeted nutrition and supplementation.
REBUILD
Muscle & Bone RecoveryFor patients with low muscle mass or low bone density who need to rebuild strength — before or after surgery. When bone density is low, muscle mass is depleted, or recovery from a previous procedure has stalled, the risk of fracture, re-injury, and surgical complication goes up. REBUILD protocols are centered on growth hormone therapy, bone-supportive nutrition, and structured strength guidance — designed to refill the tank before the next injury, surgery, or decline.
FOUNDATION
Truthe Daily FoundationDAILY FOUNDATIONTruthe Daily Foundation. Physician-formulated daily multivitamin — 120 capsules, 4 per serving, 30 servings per container. The daily baseline that supports recovery, performance, bone health, muscle preservation, and metabolic function regardless of where you are in your orthopedic journey. New patients begin here. Patients exiting RECOVER or REBUILD graduate back here. READY patients stay here throughout pre-surgical weight optimization. $69/mo.
WHAT THE RESEARCH SHOWS.
We believe you deserve honesty about what the science supports — and what it doesn't yet.
HUMAN CLINICAL TRIALS
GHK-Cu (topical)
40 years of human data. Multiple RCTs in wound healing, diabetic ulcers, post-surgical skin. Category 1 — legally compoundable today.
TB-500 / Thymosin β4
Phase 2 RCTs in chronic wounds and ophthalmic healing. RegeneRx programs RGN-259, RGN-137, RGN-352.
STRONG PRECLINICAL EVIDENCE
BPC-157
Extensive animal surgical models: tendon, ligament, bone defect, anastomosis, wound healing. 3 human pilot studies (knee pain n=12, cystitis, IV safety n=2). Every systematic review: "considered investigational."
KPV
Anti-inflammatory in gut mucosa models. Oral bioavailability via PepT1 transporter. All preclinical.
EARLY RESEARCH
LL-37
Antimicrobial peptide with prosthetic joint infection relevance. Murine wound models. No human surgical data.
CJC-1295 / Ipamorelin
GH-axis peptides with human Phase 1/2 safety data. REBUILD Tier 1 base (Growth Hormone Therapy). Available as a Provider-added Tier 2 adjunct in RECOVER after clinical review.
MOTS-c
Mitochondrial peptide. Early preclinical data in insulin resistance and exercise capacity. On the July 2026 FDA panel review list.
Semax / Selank / DSIP / Epitalon
Neuropeptides with extensive Eastern European clinical use but limited Western RCT data. Tier 2 adjuncts for sleep, anxiety, and cognition.
RECOVERY PRICING.
Nutrition Only $229. Peptides Only $399/mo. Bundle (Peptides + Nutrition) $499/mo. Final price reflects your selected tier, reviewed and approved with you before your card is charged.
HSA / FSA accepted. Ask about a Letter of Medical Necessity.
DESIGNED FOR ORTHOPEDIC PATIENTS.
FREQUENTLY ASKED QUESTIONS.
My surgeon referred me. What happens next?
Complete a brief intake form with your medical history, current condition, current medications (especially anticoagulants if post-op), and recovery timeline. A Truthe Partner Provider reviews your case within 48 hours and designs a targeted protocol. Your medication ships directly to you with complete dosing instructions.
Are these the same peptides available on research websites?
No. Research peptide vendors sell unregulated compounds labeled "research use only" — not manufactured under pharmaceutical standards, not tested for sterility, and not legal for human use. Truthe Ortho peptides are physician-prescribed, compounded by FDA-registered U.S. pharmacies with cGMP certification, and independently tested for >99% purity, sterility, and potency.
How long is a typical recovery protocol?
Most surgical recovery protocols run 8-12 weeks for soft tissue and 12-16 weeks for bone, aligned with your postoperative rehabilitation timeline. Your physician adjusts the protocol based on your recovery progress — this is not a one-size-fits-all approach.
Can I use this alongside my surgeon’s prescribed medications?
Your Truthe Ortho physician reviews your full medication list before prescribing — including anticoagulants (blood thinners), pain medications, and antibiotics. All protocols are designed to complement, never conflict with, your existing postoperative care plan. BPC-157 has documented hemostatic interactions in animal models; this is monitored.
Does my insurance cover this?
Peptide therapy is not typically covered by insurance. Most protocols qualify for HSA/FSA reimbursement under IRS Section 213(d) when prescribed for a documented medical purpose. We provide itemized receipts. RECOVER starts at $399/month. Final price reflects any Tier 2 compounds, supplements, or vitamins added by your Provider, reviewed and approved with you before your card is charged.
What if I experience a side effect?
Your Truthe Ortho care team monitors your protocol throughout. Any adverse event is documented, reported, and reviewed. You have direct messaging access to your care team. If needed, your protocol is adjusted or discontinued. We maintain a formal adverse event reporting pipeline — your safety is the non-negotiable constraint.
QUESTIONS
Questions.
We're here to help.