Effect of β-hydroxy-β-methylbutyrate (HMB) on the Muscle Strength in the Elderly Population: A Meta-Analysis
This meta-analysis aims to evaluate the effect of the emerging nutritional ingredient β-hydroxy-β-methylbutyrate (HMB) on the muscle strength of elderly people.
Lin Z, Zhao A, He J — Frontiers in nutrition
Advances in muscle health and nutrition: A toolkit for healthcare professionals
Low muscle mass and malnutrition are prevalent conditions among adults of all ages, with any body weight or body mass index, and with acute or chronic conditions, including COVID-19. This article synthesizes the latest research advancements in mus...
Prado CM, Landi F, Chew STH et al. — Clinical nutrition (Edinburgh, Scotland)
Effects of β-hydroxy β-methylbutyrate (HMB) supplementation on muscle mass, function, and other outcomes in patients with cancer: a systematic review
Low muscle mass is prevalent among patients with cancer and a predictor of adverse clinical outcomes. To counteract muscle loss, β-hydroxy β-methylbutyrate (HMB) supplementation has been proposed as a potential therapy for older adults...
Prado CM, Orsso CE, Pereira SL et al. — Journal of cachexia, sarcopenia and muscle
Nutritional interventions to improve muscle mass, muscle strength, and physical performance in older people: an umbrella review of systematic reviews and meta-analyses
Sarcopenia is a progressive and generalized skeletal muscle disorder associated with an increased risk of adverse outcomes such as falls, disability, and death. The Belgian Society of Gerontology and Geriatrics has developed evidence-based guideli...
Gielen E, Beckwée D, Delaere A et al. — Nutrition reviews
Nutrition interventions to treat low muscle mass in cancer
Many patients with cancer experience poor nutritional status, which detrimentally impacts clinical outcomes. Poor nutritional status in cancer is primarily manifested by severe muscle mass (MM) depletion, which may occur at any stage (from curativ...
Prado CM, Purcell SA, Laviano A — Journal of cachexia, sarcopenia and muscle
Beta-hydroxy-beta-methylbutyrate supplementation and skeletal muscle in healthy and muscle-wasting conditions
Beta-hydroxy-beta-methylbutyrate (HMB) is a metabolite of the essential amino acid leucine that has been reported to have anabolic effects on protein metabolism. The aims of this article were to summarize the results of studies of the effects of H...
Holeček M — Journal of cachexia, sarcopenia and muscle
The role of leucine and its metabolites in protein and energy metabolism
Leucine (Leu) is a nutritionally essential branched-chain amino acid (BCAA) in animal nutrition. It is usually one of the most abundant amino acids in high-quality protein foods. Leu increases protein synthesis through activation of the mammalian ...
Duan Y, Li F, Li Y et al. — Amino acids
Glucocorticoid-induced skeletal muscle atrophy
Many pathological states characterized by muscle atrophy (e.g., sepsis, cachexia, starvation, metabolic acidosis and severe insulinopenia) are associated with an increase in circulating glucocorticoids (GC) levels, suggesting that GC could trigger...
Schakman O, Kalista S, Barbé C et al. — The international journal of biochemistry & cell biology