G-H-K copper
A naturally occurring copper peptide that stimulates collagen, promotes skin repair, and supports hair growth.
Also known as: Copper Peptide, GHK-Copper
Last reviewed: April 2026
GHK-Cu is a small peptide naturally found in your blood. It delivers copper to cells that need it for repair and remodeling. With age, your GHK-Cu levels drop by 60%. Topical application resets skin cells' repair programming to a more youthful state — stimulating collagen, reducing inflammation, and supporting hair follicle health.
Serum or cream applied to face and scalp
Frequency
Daily (evening)
Pain Level
○○○ None
Self-Administered
Yes — at home
Typical Range
1–2% concentration
Injection for systemic effects
Frequency
Daily
Pain Level
●○○ Minimal
Self-Administered
Yes — at home
Typical Range
1mg – 2mg
Week 2–4
Skin begins to feel smoother and more hydrated.
Month 2–3
Visible improvement in skin texture, firmness, and tone.
Month 6+
Significant collagen rebuilding. Hair may appear thicker.
Overall: Mild
Mild tingling
Brief tingling on application — normal.
Skin redness
Transient redness, usually resolves quickly.
• Wilson's disease (copper metabolism disorder)
• Copper allergy
• Avoid combining with strong acids (AHAs/BHAs) at the same time — may inactivate the peptide
Pregnancy: Limited safety data in pregnancy. Avoid unless directed by provider.
GHK-Cu is the best-studied copper peptide. Works through gene expression changes rather than mechanical effects. Complements minoxidil for hair.
Minoxidil
A topical treatment that stimulates hair follicles to grow thicker, longer hair — originally developed as a blood pressure medication.
SNAP-8
A topical peptide that reduces expression lines by relaxing the muscle-nerve connection — a 'Botox in a bottle' approach.
AHK-Cu
A newer copper peptide being researched for hair growth — may stimulate follicles through a different pathway than GHK-Cu.
Interested? A licensed provider will evaluate if this is appropriate for you.
Coming Soon →This is a compounded medication prescribed off-label. It has not been FDA-approved for the uses described. All prescribing decisions are made by your independent licensed provider.