This article is due for review. Regulatory information may have changed.
Kisspeptin-10: What It Is, What the Research Has Studied, and Where It Stands
Kisspeptin-10 is a 10-amino-acid fragment of kisspeptin, a hormone produced in the hypothalamus.
ReviewThe Short Version
Kisspeptin-10 is a 10-amino-acid fragment of kisspeptin, a hormone produced in the hypothalamus that acts on reproductive hormone signaling. It has been studied in clinical research at academic centers. Kisspeptin-10 is not FDA-approved.
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Where It Comes From
Kisspeptin is encoded by the KISS1 gene. Kisspeptin-10 is the shortest fragment that retains activity at the kisspeptin receptor (KISS1R, also called GPR54).
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Mechanisms Studied
Research has examined kisspeptin-10 in connection with gonadotropin-releasing hormone (GnRH) signaling and the downstream release of luteinizing hormone and follicle-stimulating hormone.
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Research Status
Academic centers have studied kisspeptin-10 in clinical research on reproductive hormone signaling, including research on its possible use as a diagnostic test of hormone signaling. These studies have been small, and its uses in people have not been established in large trials.
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Safety Information
Clinical studies have reported on short-term safety in small numbers of participants. Long-term safety data are limited.
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Regulatory Status
Kisspeptin-10 was removed from the FDA's Category 2 list and has not been added to the 503A bulks list. It is not an FDA-approved drug.
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*This article represents the analysis of the author based on publicly available research. It is not medical advice, does not constitute a recommendation for or against any compound, and should not replace consultation with a licensed healthcare provider.*
This content is for educational and informational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a licensed healthcare provider before starting any peptide therapy or making changes to your health protocol.