five amino one M-Q
A small molecule that blocks an enzyme responsible for fat storage — may support weight loss by shifting metabolism toward fat burning.
Last reviewed: April 2026
5-Amino-1MQ inhibits an enzyme called NNMT that plays a role in fat cell metabolism. When NNMT is overactive, your body preferentially stores fat. By blocking it, 5-Amino-1MQ shifts metabolism toward fat burning and may support lean muscle preservation.
Capsule taken daily
Frequency
1–2 times daily
Pain Level
○○○ None
Self-Administered
Yes — at home
Typical Range
50mg – 150mg daily
Month 1
Metabolic effects begin. May complement diet efforts.
Month 2–3
Improved body composition alongside diet and exercise.
Overall: Mild
GI discomfort
Mild stomach upset.
Headache
Usually transient.
• Pregnancy
• Liver or kidney disease
• Limited human safety data
• Limited interaction data — inform provider of all medications
Pregnancy: Not studied in pregnancy. Avoid.
Different mechanism from GLP-1 agonists. 5-Amino-1MQ targets fat cell metabolism directly; GLP-1 agonists target appetite. Can be complementary.
Semaglutide
A medication that reduces appetite and helps your body lose weight by mimicking a natural gut hormone.
AOD-9604
A modified fragment of growth hormone that targets fat burning without the growth-promoting side effects of full GH.
We don't currently offer this peptide — but we have protocols for similar goals.
Coming Soon →This is a compounded medication prescribed off-label. It has not been FDA-approved for the uses described. All prescribing decisions are made by your independent licensed provider.