5-Amino-1MQ
five amino one M-Q
A small molecule that blocks an enzyme responsible for fat storage — may support weight loss by shifting metabolism toward fat burning.
Last reviewed: April 2026
What It Does
5-Amino-1MQ inhibits an enzyme called NNMT that plays a role in fat cell metabolism. When NNMT is overactive, your body preferentially stores fat. By blocking it, 5-Amino-1MQ shifts metabolism toward fat burning and may support lean muscle preservation.
Why People Take It
How It's Administered
Oral
Capsule taken daily
Frequency
1–2 times daily
Pain Level
○○○ None
Self-Administered
Yes — at home
Typical Range
50mg – 150mg daily
What To Expect
Month 1
Metabolic effects begin. May complement diet efforts.
Month 2–3
Improved body composition alongside diet and exercise.
Side Effects
Overall: Mild
Uncommon (0.1–1%)
GI discomfort
Mild stomach upset.
Headache
Usually transient.
Who Should NOT Take This
• Pregnancy
• Liver or kidney disease
• Limited human safety data
Drug Interactions
• Limited interaction data — inform provider of all medications
Pregnancy: Not studied in pregnancy. Avoid.
Clinical Details
Compare With Similar Peptides
Different mechanism from GLP-1 agonists. 5-Amino-1MQ targets fat cell metabolism directly; GLP-1 agonists target appetite. Can be complementary.
Semaglutide
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AOD-9604
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Frequently Asked Questions
We don't currently offer this peptide — but we have protocols for similar goals.
Coming Soon →This is a compounded medication prescribed off-label. It has not been FDA-approved for the uses described. All prescribing decisions are made by your independent licensed provider.